Osteodystrophy in chronic liver diseases

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Osteodystrophy in chronic liver diseases.

Osteoporosis and osteomalacia are, to date, among the most common metabolic diseases in the world. Lately, an association between metabolic bone diseases and chronic liver disease has been increasingly reported, inducing many authors to create a new nosographic entity known as 'hepatic osteodystrophy.' The importance of such a condition is further increased by the morbidity of these two disease...

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Ramadan is a sacred month for Muslims all around the world. During this lunar-based month, healthy adult Muslims are obligated to abstain from eating, drinking, smoking, or using oral medications from predawn to sunset. Followers will typically eat just after sunset and again before dawn (1). The Islamic lunar Hijri calendar is 11 days shorter than the Gregorian solar calendar, and therefore, t...

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Hepatic osteodystrophy and liver cirrhosis.

AIM To investigate the correlation between hepatic osteodystrophy and osteoporosis in patients with liver cirrhosis. METHODS Bone mineral density of the patients (n = 55) and that of the control group (n = 30) were measured by dual-energy X-ray absorptiometry. All the women in the study were premenopausal. Deoxypyridinoline, pyridinoline and urinary Ca(2+) were measured as bone destruction ma...

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Osteodystrophy in Cholestatic Liver Diseases Is Attenuated by Anti-γ-Glutamyl Transpeptidase Antibody

BACKGROUND Cholestatic liver diseases exhibit higher levels of serum γ-glutamyl transpeptidase (GGT) and incidence of secondary osteoporosis. GGT has been identified as a novel bone-resorbing factor that stimulates osteoclast formation. The aim of this study was to elucidate the interaction of elevated GGT levels and cholestatic liver disease-induced bone loss. METHODS Wistar rats were divide...

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Angiogenesis and Fibrogenesis in Chronic Liver Diseases

Pathologic angiogenesis appears to be intrinsically associated with the fibrogenic progression of chronic liver diseases, which eventually leads to the development of cirrhosis and related complications, including hepatocellular carcinoma. Several laboratories have suggested that this association is relevant for chronic liver disease progression, with angiogenesis proposed to sustain fibrogenes...

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ژورنال

عنوان ژورنال: Internal and Emergency Medicine

سال: 2012

ISSN: 1828-0447,1970-9366

DOI: 10.1007/s11739-012-0753-5